put a few drops of the oil under your tongue.Oral CBD is less likely to cause side effects than vaping, so some beginners may want to start there. Some of these uses include the management of: Neither drug had a significant impact on the frequency of migraine attacks, which the researchers attributed to the short duration of the study.Īlthough lawmakers in the United States are currently debating the merits of cannabis and related products, the plant’s medicinal uses aren’t a new discovery.Īccording to the National Center for Complementary and Integrative Health (NCCIH), cannabis has been used in alternative medicine for over 3,000 years. Using nabilone resulted in less intense pain as well as lowered drug dependence. However, at the end of the study, participants reported more improvements and better quality of life when taking nabilone. Then they switched to the other drug for the final eight weeks.īoth drugs proved to be effective. 50 mg a day of nabilone or 400 mg a day of ibuprofen.Īfter taking one drug for eight weeks, the study participants went without medication for one week. Twenty-six people who experienced medication overuse headaches began by taking oral doses of either. Study on nabiloneĪ 2012 Italian study explored the effects of nabilone, a synthetic form of THC, on headache disorders. People in the migraine and headache subgroups preferred OG Shark, a hybrid strain with high levels of THC and low levels of CBD. Most participants were able to replace their prescription medications - typically opioids or opiates - with cannabis.Īll subgroups preferred hybrid strains of cannabis. People who used edible marijuana, as opposed to inhaling it or using other forms, experienced the most side effects.Ī 2018 study looked at 2,032 people with migraine, headache, arthritis, or chronic pain as a primary symptom or illness. Researchers found that of the 48 people surveyed, 39.7 percent reported fewer migraine attacks overall.ĭrowsiness was the biggest complaint, while others had difficulty figuring out the right dose. In 2016, Pharmacotherapy published a study on the use of medical marijuana for migraine. Research on other forms of cannabis may provide additional hope for those seeking migraine pain relief. The researchers concluded that cannabinoids were only effective against acute cluster headaches if a person had experienced migraine attacks as a child. This drop in pain intensity was only observed in participants who’d had migraine attacks that began in childhood. However, some did see their pain intensity drop by 43.5 percent. Participants with cluster headaches only saw a slight decrease in the severity and frequency of their headaches. The THC-CBD combination also reduced the intensity of the pain by 43.5 percent. The THC-CBD combination reduced migraine attacks by 40.4 percent, while amitriptyline led to a 40.1 percent reduction in migraine attacks. The treatment period lasted for three months, and a follow-up occurred four weeks after treatment ended. The 48 people with cluster headaches received a daily dose of 200 mg of the THC-CBD combination from phase I or 480 mg of verapamil, a calcium channel blocker. The 79 people with chronic migraine received a daily dose of 200 mg of the THC-CBD combination from phase I or 25 mg of amitriptyline, a tricyclic antidepressant.
Phase II of the study looked at people with chronic migraine or cluster headaches. When doses were increased to 200 mg, acute pain was reduced by 55 percent. The compounds were administered orally.ĭoses under 100 milligrams (mg) had no effect. One compound contained 19 percent THC, while the other contained 9 percent CBD and virtually no THC. In phase I of their study, 48 people with chronic migraine received a combination of two compounds.
In 2017, at the 3rd Congress of the European Academy of Neurology (EAN), a group of researchers presented the results of their study on cannabinoids and migraine prevention. Still, some laboratory studies have suggested that CBD oil may help all forms of chronic and acute pain, including migraine. This limited research is due, in part, to regulations on CBD and obstacles with cannabis legalization. There are currently no published studies that examine the effects of CBD as a single ingredient on migraine. Existing studies look at the combined effects of CBD and tetrahydrocannabinol (THC), a different cannabinoid. Research on the use of CBD for migraine is limited.
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